Advanced longitudinal analysis of repeated blood marker measurements in a population-based setting

Comparison and development of methods to longitudinally analyze blood marker concentrations (hsCRP, insulin, glucose, HbA1c) taking measurement error, loss to follow-up and medication intake into account.

Default longitudinal analysis approaches are not appropriate as in addition to the usage of different measurement techniques several important aspects need to be taken into account: age structure of the participants, selection bias due to study drop outs and intake of medication affecting the blood markers. Therefore, this project shall compare and develop methods which can account for the different aspects. Additional information on socio-demographic, lifestyle and clinical characteristics is available for all participants and time points and will be provided.

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